Basic Information
VIS ID
TVIS44024011
Fusion event
HTLV-1-SEC1P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49146914/48643657 (Hg38)
End
49146914/48643657 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA19A
Target gene
SEC1P
Nearest miRNA
hsa-mir-10395/Upstream/1416636; hsa-let-7e/Downstream/366249;
Nearest TSS
ENST00000633603/Upstream/4198; ENST00000522283/Downstream/2655;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5783, chr19-CpG: 66/Downstream/17841
Upstream sequence
aatttgaggttacagtgagctatgactgggccactgcactccagcctgggtcacagagtgagatcccaattccaaaaaaaaaaaaaaaaaGTATGGTTCC
Downstream sequence
Cagcatggtactataaagcaggtcccagcattcatgctacgctgcttggtttgaatgccagtgctggctctctgtgtgatcctaggcaagtaacttaacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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