VISDB Viral Integration Site DataBase

VIS ID

TVIS44024013

Fusion event

HTLV-1-MYH14 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

q13.33

Reference genome

Start

End

50775607/50272350 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-412-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-4728-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6760-5p ; hsa-mir-4428 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-9500 ; hsa-mir-1275 ; hsa-mir-2467-3p ; hsa-mir-3127-5p ; hsa-mir-363-5p ; hsa-mir-4271 ; hsa-mir-4506 ; hsa-mir-4525 ; hsa-mir-4651 ; hsa-mir-4665-5p ; hsa-mir-4693-3p ; hsa-mir-4723-5p ; hsa-mir-4725-3p ; hsa-mir-5000-5p ; hsa-mir-5010-5p ; hsa-mir-5192 ; hsa-mir-5680 ; hsa-mir-5698 ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-6716-5p ; hsa-mir-6745 ; hsa-mir-6780b-5p ; hsa-mir-6782-5p ; hsa-mir-6798-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-8071

Nearest miRNA

hsa-mir-10395/Upstream/339213; hsa-let-7e/Downstream/934579;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/13055, chr19-CpG: 17/Downstream/36690

Upstream sequence

CTGTTGACTTAGAATCAGAAACAGAAGGGAAGGGGCACAGGGAGGAGGCAGGGCTGTAGACACAGGGCAGAGAGAGTCAGAGGGTGGAGGCATGGGCTGT

Downstream sequence

TGGTGGGGATGAGGAGGAGAGGACAGTGCGTCTAGGACAACATTGTGGGAAGAGTCCCTGAGATAGATGGGGAAGGTGGGAGGAGGAGAAGGCGTTAAGG