Basic Information
VIS ID
TVIS44024016
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
5355471/5355460 (Hg38)
End
5355471/5355460 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1227/Upstream/422720; hsa-let-7e/Downstream/1034178;
Nearest TSS
ENST00000633603/Upstream/14657; ENST00000222033/Downstream/99971;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/14410, chr19-CpG: 74/Downstream/100010
Nearby gene
PTPRS(-14657) ;
Upstream sequence
cactgttcctggggctttgcaatgacccctgccctcgcagtcctaggtctgtgctgttactgccatattttatgggcgagacgcagaaagcctgagcacc
Downstream sequence
agcccatgcctgcacaacACAGCCAGGACTGGAAACTGTCTCTGGGCAAAGGCTGTCCCTAGGTCTCTGGTGGGAGCCCGCTCTGCCCTCAAATCAAGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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