Basic Information
VIS ID
TVIS44024052
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
23833112/23852475 (Hg38)
End
23833112/23852475 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/5381784; hsa-mir-1-1/Downstream/2355711;
Nearest TSS
ENST00000382410/Upstream/25744; ENST00000457274/Downstream/27275;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/214426, chr20-CpG: 25/Downstream/136037
Nearby gene
CST5(-23460) ;
Nearest cancer related gene
CST5(TSG, -23460) ;
Upstream sequence
gttttgtttttttctgaccctagtcaaaaaaggaagttttattctattggaaatgtagtcagtattatggcatataaaataattagtgcaccatacagtt
Downstream sequence
gtttttatttttgatgggagttgaatgagatagaatttctcaatttttgacatttgtagggcacagatctgtgtggtgaaactacccatagtaaggacac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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