VISDB Viral Integration Site DataBase

VIS ID

TVIS44024057

Fusion event

HTLV-1-PLAGL2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q11.21

Reference genome

Start

End

30782101/32194298 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-122-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-24-3p ; hsa-mir-296-3p ; hsa-mir-548q ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-548n ; hsa-mir-4311 ; hsa-mir-3681-3p ; hsa-mir-3613-3p ; hsa-mir-513a-5p ; hsa-mir-145-5p ; hsa-mir-5195-3p ; hsa-mir-4468 ; hsa-mir-205-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-1255b-5p ; hsa-mir-3925-3p ; hsa-mir-1255a ; hsa-mir-766-3p ; hsa-mir-335-5p ; hsa-mir-6732-5p ; hsa-mir-6079 ; hsa-mir-4762-3p ; hsa-mir-3190-3p ; hsa-mir-4650-3p ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-15b-3p ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-545-5p ; hsa-mir-759 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-595 ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-mir-502-5p ; hsa-mir-545-3p ; hsa-mir-4496 ; hsa-mir-634 ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-943 ; hsa-mir-4711-3p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-7162-3p ; hsa-mir-6134 ; hsa-mir-4649-3p ; hsa-mir-892a ; hsa-mir-553 ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-3134 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-8062 ; hsa-mir-2278 ; hsa-mir-4796-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6734-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4283 ; hsa-mir-4437 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-7-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6085 ; hsa-mir-6813-5p ; hsa-mir-548f-5p ; hsa-mir-1228-3p ; hsa-mir-34b-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-6716-5p ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-5189-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-218-2-3p ; hsa-mir-1246 ; hsa-mir-138-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-184 ; hsa-mir-3616-3p ; hsa-mir-3665 ; hsa-mir-4436b-3p ; hsa-mir-4632-5p ; hsa-mir-4710 ; hsa-mir-4736 ; hsa-mir-552-3p ; hsa-mir-570-3p ; hsa-mir-577 ; hsa-mir-6721-5p ; hsa-mir-6735-5p ; hsa-mir-6758-5p ; hsa-mir-6856-5p ; hsa-mir-6879-5p ; hsa-mir-6880-5p ; hsa-mir-7843-5p ; hsa-mir-7845-5p ; hsa-mir-126-3p ; hsa-mir-1321 ; hsa-mir-182-5p ; hsa-mir-203a-3p ; hsa-mir-224-3p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-31-5p ; hsa-mir-3650 ; hsa-mir-3689d ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-522-3p ; hsa-mir-6809-5p ; hsa-mir-6851-5p ; hsa-mir-7854-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/587058; hsa-mir-1-1/Downstream/43497;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/3772, chr20-CpG: 87/Downstream/13181

Nearest cancer related gene

PLAGL2(OG, No orient, 0)

Upstream sequence

GTAGGGAAGGTGGCAGTTAAGGTGAGAAGGGTTGCTGAGTCTAGTGATGAAAACCAGATACAACAAAGAGGATGGCAACAGCGAGTCCCAACTGGATTCT

Downstream sequence

CACATACCATCACCTATAATACAAGTCCCAATAACATGCACAGCATGCAGGAGGTGGCTGCGTACCAAGGTAGACACTTTTTAAAATAAACCTTAATTAG