Basic Information
VIS ID
TVIS44024075
Fusion event
HTLV-1-SLC13A3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
45232743/46604104 (Hg38)
End
45232743/46604104 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC13A3
Nearest miRNA
hsa-mir-103a-2/Upstream/898924; hsa-mir-1-1/Downstream/562863;
Nearest TSS
ENST00000382410/Upstream/3488; ENST00000606362/Downstream/9621;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/90406, chr20-CpG: 83/Downstream/84948
Upstream sequence
aagacagaaagaaTTTAACAGGAAGCTGAGTACTAGCAAATGTTCAGTAAATATGGGTTACCATAGAGAAAGAAGAAAACAGAGCATAGGGAATGATTCT
Downstream sequence
GACACTCAGAGCCTGGTCACTTCATTCTCCATCATCTTGTCTAAGGGCAAGGTGGCTGTGTCACCCTCaaaatcccaacatccccctctcttgctaaatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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