Basic Information
VIS ID
TVIS44024076
Fusion event
HTLV-1-RPL35AP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
46107705/47478961 (Hg38)
End
46107705/47478961 (Hg38)
Orient
-
Location type
Intronic
Target gene
RPL35AP
Nearest miRNA
hsa-mir-103a-2/Upstream/311903; hsa-mir-1-1/Downstream/2384898;
Nearest TSS
ENST00000382410/Upstream/66634; ENST00000490248/Downstream/22941;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/239594, chr20-CpG: 56/Downstream/22723
Nearby gene
NCOA3(+22896) ;
Upstream sequence
caggaggcggaggttgcagtaagccgagattgtgccattgcactccagcctgggtgacagagtgaaagtccgtgtcaaaaaaaaaaaaaaagaaaaaaaa
Downstream sequence
gtaaaaGGAAAAAAGGAAAAATGGCCTTAGACCACAGCCTTCCAGACATATCTGCCTTTTAGAAGTCCTGTCCTggttgggcagggtgtctcatgtcagt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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