Basic Information
VIS ID
TVIS44024084
Fusion event
HTLV-1-ZFP64 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
50720751/52104212 (Hg38)
End
50720751/52104212 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZFP64
miRNAs that regulate target gene
hsa-mir-320a ; hsa-mir-196a-5p ; hsa-mir-138-1-3p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-3679-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-4286 ; hsa-mir-361-3p ; hsa-mir-483-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/651235; hsa-mir-1-1/Downstream/1964196;
Nearest TSS
ENST00000382410/Upstream/5625; ENST00000454600/Downstream/638;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/19019, chr20-CpG: 61/Downstream/559
Upstream sequence
CCACGGGGAGCTGGCAGCCTAAGAGAAAGTAGGAACCTACAATCTCTTAATCTAAGCACAAGATAAGCAAAAAGGGAAGCGCCTTAGAAATGCAGATTCC
Downstream sequence
CCAACCCCACCCCTGAGATTCCAGTGGAGGCGGGGGATGGGGGGATCCCTAACTTGCAGGAAGAATTTGGCGAGCGAGAAAAGGTCCCCTCCCGCAGGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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