Basic Information
VIS ID
TVIS44024101
Fusion event
HTLV-1-GTF2IP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
14829088/13456767 (Hg38)
End
14829088/13456767 (Hg38)
Orient
-
Location type
Intronic
Target gene
GTF2IP2
Nearest miRNA
hsa-mir-10396a/Upstream/50307; hsa-let-7c/Downstream/188008;
Nearest TSS
ENST00000624081/Upstream/151615; ENST00000427446/Downstream/89266;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/2829043, chr21-CpG: 39/Downstream/152848
Nearby gene
MIR3156-3(-50307) ;
Upstream sequence
gtaaccaaatgtgacacagagaaccaaagagagcacacgctgttggaaaaatggcacaaaagacttgacaaaagattcccacaaatcttcaatttataaa
Downstream sequence
aactgcagtatctgcagggctcaaaaaaatgaGTTATGCCTGTATGTATTCTGTGCCTATCGCCCTGCCTTTTTTAGTTCCCTTTCAGTGTTTCACTCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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