Basic Information
VIS ID
TVIS44024107
Fusion event
HTLV-1-LOC101927745 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
16749693/15377374 (Hg38)
End
16749693/15377374 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA21A
Target gene
LOC101927745
Nearest miRNA
hsa-mir-10396a/Upstream/1653100; hsa-let-7c/Downstream/1161715;
Nearest TSS
ENST00000624081/Upstream/310304; ENST00000464435/Downstream/24931;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/311831, chr21-CpG: 123/Downstream/352160
Nearby gene
NRIP1(-312567) ;
Upstream sequence
AACTGAAAGGCTGGACTCAATGTCCAAGATATAGGTAATGCATGCGCCAGGTATATACTCAACTACTATGAAATTATTCCTAACTCAGGCCTGGAGATGG
Downstream sequence
GTTATGGAACCTGGAAGAAACGCTCAGTTGTCTGATTTGAAAGTGCAAAGGCCAGTGCTTACTCAGAAACACTGCTAAGTGTCCCACAAAACTGGTGAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate