Basic Information
VIS ID
TVIS44024109
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
20575631/19203313 (Hg38)
End
20575631/19203313 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/517149; hsa-mir-155/Downstream/3875971;
Nearest TSS
ENST00000624081/Upstream/72790; ENST00000433210/Downstream/98300;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/957756, chr21-CpG: 89/Downstream/1793792
Nearby gene
MIR548XHG(No orient, 443501)
Upstream sequence
aagaaatggtaaatgtttgaggtgatggatatgctaattactctaatttaatcttacacactgtatgcaatgcatcaaaatatcacactgtaccccataa
Downstream sequence
atatgtataataattatgtgttaattaaaaatGTTGATAATGACCAAAAAAAGAAAGGATACCAGACATGTGTGTGcacagaggagagaccatttgagga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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