Basic Information
VIS ID
TVIS44024131
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
40071580/38699656 (Hg38)
End
40071580/38699656 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/2978848; hsa-mir-3197/Downstream/747354;
Nearest TSS
ENST00000624081/Upstream/37876; ENST00000432278/Downstream/42397;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/37915, chr21-CpG: 151/Downstream/105422
Nearby gene
ERG(-37876) ;
Nearest cancer related gene
ERG(OG, -37876) ;
Upstream sequence
CTGTAAGACAAGGCCAATGCCTGAGACAGACAGTAGCCACCACTCCAGTGTCACTTAGATCTCTCTAAAGACAGAAAAGTAAGGAAAGAACCCAGAGTTC
Downstream sequence
CATCAGGCAGAAAATAATTGAGAGAAGGAAACTTGCTGAAACCTTAATAGGATGCCTTCAAGCTACACAAATCAGACGGAATAGTTAGGTAATGGTAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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