VISDB Viral Integration Site DataBase

VIS ID

TVIS44024136

Fusion event

HTLV-1-BACE2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr21

Cytoband

q22.2

Reference genome

Start

End

42563962/41192035 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-2054 ; hsa-mir-1299 ; hsa-mir-3686 ; hsa-mir-4662a-5p ; hsa-mir-5189-3p ; hsa-mir-3607-3p ; hsa-mir-4778-5p ; hsa-mir-3651 ; hsa-mir-1277-5p ; hsa-mir-302c-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-6733-5p ; hsa-mir-211-3p ; hsa-mir-7845-5p ; hsa-mir-5584-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-583 ; hsa-mir-6868-3p ; hsa-mir-670-5p ; hsa-mir-2277-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-1207-3p ; hsa-mir-141-5p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3149 ; hsa-mir-3912-5p ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6755-3p ; hsa-mir-198 ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-4716-5p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-483-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-4448 ; hsa-mir-6861-3p ; hsa-mir-6821-3p ; hsa-mir-3182 ; hsa-mir-149-5p ; hsa-mir-4794 ; hsa-mir-664a-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4723-3p ; hsa-mir-6769b-3p ; hsa-mir-3183 ; hsa-mir-6800-3p ; hsa-mir-3064-5p ; hsa-mir-6504-5p ; hsa-mir-1226-5p ; hsa-mir-25-5p ; hsa-mir-3616-3p ; hsa-mir-433-5p ; hsa-mir-4487 ; hsa-mir-4710 ; hsa-mir-4721 ; hsa-mir-4730 ; hsa-mir-553 ; hsa-mir-7160-3p

Nearest miRNA

hsa-let-7c/Upstream/24406; hsa-mir-5692b/Downstream/554737;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/23090, chr21-CpG: 16/Downstream/53855

Upstream sequence

tttgtcaccaattttccaatcatgcttcttccaattccctgatgatccagccaaaccattggctacggcccatgaatcagtgtataatcacacagctggc

Downstream sequence

catttctccttccatgcaaagtgcacaaccaggtgcactgctcgaagttctgcccactgggaagatttcccttcactgctgtccttcatggatgccctag