Basic Information
VIS ID
TVIS44024139
Fusion event
HTLV-1-PDE9A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
44137402/42717292 (Hg38)
End
44137402/42717292 (Hg38)
Orient
-
Location type
Intronic
Target gene
PDE9A
Nearest miRNA
hsa-let-7c/Upstream/970451; hsa-mir-5692b/Downstream/233636;
Nearest TSS
ENST00000624081/Upstream/31095; ENST00000466472/Downstream/14466;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/30856, chr21-CpG: 27/Downstream/120564
Upstream sequence
atatcccttcactctaaagcatttcttttttcttttaatgtttcttgcagtgcatatctgctagtaactaattctctcagcttttgctgattggaacatg
Downstream sequence
ccttttttttttttttttttttttgaaatgatgtcttgctctgtcgcccaggttggagtgtacaatcagttcactgcaacctccgcctcctaggttcaag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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