Basic Information
VIS ID
TVIS44024142
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
46239228/44819313 (Hg38)
End
46239228/44819313 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1209324; hsa-mir-6815/Downstream/658953;
Nearest TSS
ENST00000624081/Upstream/534; ENST00000609694/Downstream/42620;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/270, chr21-CpG: 27/Downstream/29668
Nearby gene
SUMO3(-1184) ;
Upstream sequence
TTCTTGGCTAGAGCCCCCACTTAGGAGGGGGAAGGCTGCTGAAGTCTTTCGGGGAGAGGGTCTGAGAGTCAGCCCCAGTCCCAGGCAGGTCATAAGGTGT
Downstream sequence
GGTCCCTTCCTTCTGGAACCTGGAGCCCAGGGCCTCAGCAGAGGATGTGGAGGTGGGTGGCCAGCTCAGACGGTCCTGGGAGGGGGCTCCGCAACCAGCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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