Basic Information
VIS ID
TVIS44024153
Fusion event
HTLV-1-IGLL4P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
20987108/20632821 (Hg38)
End
20987108/20632821 (Hg38)
Orient
-
Location type
Intronic
Target gene
IGLL4P
Nearest miRNA
hsa-mir-1286/Upstream/383610; hsa-let-7a-3/Downstream/401355;
Nearest TSS
ENST00000624155/Upstream/47875; ENST00000406799/Downstream/80172;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/47755, chr22-CpG: 77/Downstream/34901
Nearby gene
MED15(+45189) ;
Upstream sequence
TGAAGACTGCCACACCCTCCAAACAGAGAAACACAAGTACACGGTTAGCAGCTACCTGAACCTGACGTCTGACCAGTGGAGGTCCCCCAGCAGCTATGTT
Downstream sequence
CTTAGGCCCCTCACCCCACCCACAGCAGCCAGGAGCTGCAGGATCCCAGGGCAGGGGTCTCCCCTCCCACCCCAAGGCATCCAGCCCTTCTCCTTGCACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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