Basic Information
VIS ID
TVIS44024164
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
31785614/31389628 (Hg38)
End
31785614/31389628 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA22B
Nearest miRNA
hsa-mir-1286/Upstream/229509; hsa-let-7a-3/Downstream/231839;
Nearest TSS
ENST00000624155/Upstream/42742; ENST00000486584/Downstream/9895;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/41907, chr22-CpG: 69/Downstream/9636
Nearby gene
DRG1(+9925) ;
Upstream sequence
ccttcccttccttttccttttaagacaaggtctcgttttgttgcccaggctgcaaagatgcaatcctggctcatttcaacctctgcttgccgatctcaag
Downstream sequence
tgatttcccacctcaatctgctgagtagctgggactacagtaacatgctaccacgaccagttaattctggtattttttgtagagatggagttttgccatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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