Basic Information
VIS ID
TVIS44024173
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
35854936/35458943 (Hg38)
End
35854936/35458943 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1286/Upstream/122144; hsa-let-7a-3/Downstream/827904;
Nearest TSS
ENST00000624155/Upstream/47504; ENST00000610000/Downstream/67989;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/34634, chr22-CpG: 143/Downstream/80991
Nearby gene
MCM5(+34441) ;
Upstream sequence
TCCCAGTGGGGTCACACCACCAGGAAGGGACAGGGCAAGGCCCCACGCCCAGGTCTGCACCACCCCTGAGGCTGAGTGCCTGTCCACACTCCACATCACA
Downstream sequence
CCGTCTGGGACCTCAGGCCGGGTAGGAGACAGGAGTCCCTGAGGGTCAAACATCTGGAGAGAAAGAAGAGACGGGAAGACCAAGAGGCTCTTGCTGCATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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