VISDB Viral Integration Site DataBase

VIS ID

TVIS44024175

Fusion event

HTLV-1-APOL6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q12.3

Reference genome

Start

End

36045602/35649555 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-6811-3p ; hsa-mir-668-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-4999-3p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-6867-5p ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-96-3p ; hsa-mir-2681-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-3163 ; hsa-mir-4668-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4313 ; hsa-mir-3927-5p ; hsa-mir-4286 ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-1281 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-340-5p ; hsa-mir-643 ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-665 ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-589-5p ; hsa-mir-6746-5p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-3140-3p ; hsa-mir-943 ; hsa-mir-630 ; hsa-mir-4742-3p ; hsa-mir-133a-3p ; hsa-mir-874-3p ; hsa-mir-5006-5p ; hsa-mir-3972 ; hsa-mir-1202 ; hsa-mir-4281 ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-7976 ; hsa-mir-3194-5p ; hsa-mir-7152-3p ; hsa-mir-18a-3p ; hsa-mir-6752-3p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6779-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4778-3p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-3190-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3926 ; hsa-mir-4684-5p ; hsa-mir-4724-5p ; hsa-mir-548s ; hsa-mir-606 ; hsa-mir-6771-3p ; hsa-mir-6849-3p ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-143-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-615-5p ; hsa-mir-6758-3p ; hsa-mir-6890-5p ; hsa-mir-7704 ; hsa-mir-8055

Nearest miRNA

hsa-mir-1286/Upstream/312756; hsa-let-7a-3/Downstream/637292;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/97606, chr22-CpG: 131/Downstream/378616

Upstream sequence

ctagggaggttatcttgaagctgtgttttcaaagtaagcagatttttcttacttagattgtgtatctgcagaagttggttttgtgggggAAGGCAGGTAA

Downstream sequence

GGAAAGACTGTCATAAATATCCTGTAAGCTTTCAAATGAAAGTAAGTTCTCAAATCCTCTTCCAATAAACCTCTCACAAGCAAATCCTCTCGCAACCACC