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TVIS44024184
Basic Information
VIS ID
TVIS44024184
Fusion event
HTLV-1-SH3BP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
38041429/37645422 (Hg38)
End
38041429/37645422 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA22A
Target gene
SH3BP1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-26b-5p
;
hsa-mir-218-5p
;
hsa-mir-1249-5p
;
hsa-mir-1321
;
hsa-mir-1343-5p
;
hsa-mir-149-3p
;
hsa-mir-3150a-3p
;
hsa-mir-3175
;
hsa-mir-342-5p
;
hsa-mir-4419a
;
hsa-mir-4510
;
hsa-mir-4664-5p
;
hsa-mir-4728-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-491-5p
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6732-5p
;
hsa-mir-6752-5p
;
hsa-mir-6763-5p
;
hsa-mir-6785-5p
;
hsa-mir-6797-5p
;
hsa-mir-6825-5p
;
hsa-mir-6842-5p
;
hsa-mir-6883-5p
;
hsa-mir-7110-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-939-5p
Nearest miRNA
hsa-mir-1286/Upstream/1358515; hsa-let-7a-3/Downstream/198850;
Nearest TSS
ENST00000624155/Upstream/1708;
ENST00000466097/Downstream/1346;
Nearest CpG islands
None/Target,
chr22-CpG: 279/Upstream/5501
,
chr22-CpG: 133/Downstream/12974
Upstream sequence
GGTGGGAAGGCCCTGGGCCGCTGATCTGTTTCATCCCTGCAGACCACTCCCCTTCGATGACAGCCACCCACTTCCCCAGGGTGTATGGGGTGTCGCTGGC
Downstream sequence
AACCCACCTGCAAGAGCTGGGCCGGGAGATTGCCCTGCCCATCGAGGCCTGCGTCATGATGCTGCTTTCTGAGGGCATGAAGGAAGAGGTGGGGTCCCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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