Basic Information
VIS ID
TVIS44024203
Fusion event
HTLV-1-ARMCX5-GPRASP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
101906687/102651759 (Hg38)
End
101906687/102651759 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARMCX5-GPRASP2
Nearest miRNA
hsa-let-7f-2/Upstream/7588533; hsa-mir-105-1/Downstream/3988055;
Nearest TSS
ENST00000429181/Upstream/358; ENST00000466098/Downstream/1087;
Nearest CpG islands
chrX-CpG: 89/Target, None/Upstream, None/Downstream
Upstream sequence
GGCAACCTGCCCCCCGGACCCTGACAGCCTGGCAACGAGGAGACGATCCGTTCGGAGCCGGGCGCTAGAGAGAGGTGCGCAGTGCCCGAGATCCCTGGCT
Downstream sequence
ATGGGGAGGCGGTGACTGGTGCGGGCCAGGCCGGACCAAGGGCTGAGGGGCTGGCTCCAGAGGCACCGTCAGATCGTCTGGAGGAGAACCGCGCTGACCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate