Basic Information
VIS ID
TVIS44024233
Fusion event
HTLV-1-SPANXN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
142605134/143517306 (Hg38)
End
142605134/143517306 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRAXA
Target gene
SPANXN3
Nearest miRNA
hsa-let-7f-2/Upstream/2591075; hsa-mir-105-1/Downstream/2475444;
Nearest TSS
ENST00000429181/Upstream/232329; ENST00000423667/Downstream/169;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2340086, chrX-CpG: 130/Downstream/116288
Upstream sequence
ccacttccacaggtgtctgcagtattcctgtgttgctgtttgagccaccccctctctgtgtgtctttctttcaccctcaccttcccttcaaaacctgaca
Downstream sequence
ATCTTACCTCATCATTTTTTTTGTTATTGGATTCACAGGGGCTCTTCGTCTTCTCCCCATTGGTGCTGGAAGTTGGCTGTTCCATGATTCTGGTTGGTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate