Basic Information
VIS ID
TVIS44024237
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
149364171/150195941 (Hg38)
End
149364171/150195941 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRAXE ; FRAXF
Nearest miRNA
hsa-let-7f-2/Upstream/2911213; hsa-mir-105-1/Downstream/32063;
Nearest TSS
ENST00000429181/Upstream/179859; ENST00000358892/Downstream/165481;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/257236, chrX-CpG: 356/Downstream/165332
Nearby gene
MIR2114(+32068) ;
Upstream sequence
GAGGAAAGAAGACTTCTCAAGAAGTCAGAAACATGCTACTATCTGTTGCTTCAGGAAGAAGGGAGATGGAGACTGAGGTTCCTTTAGATGGTGGCATACC
Downstream sequence
AGGAGAGACTGGATGGCCACAGAGCAGGAATGTCACAGGAGCAGGAAACTTCAAGTGGCAACCACGTCCAGACCCAAGCCTCTGGGGTGTCTAGAGTGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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