VISDB Viral Integration Site DataBase

VIS ID

TVIS44024240

Fusion event

HTLV-1-VMA21 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chrX

Cytoband

q28

Reference genome

Start

End

150566018/151397546 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRAXE ; FRAXF

Target gene

miRNAs that regulate target gene

hsa-mir-331-3p ; hsa-mir-93-5p ; hsa-mir-16-5p ; hsa-mir-18a-3p ; hsa-mir-330-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-122-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-624-5p ; hsa-mir-1233-5p ; hsa-mir-3659 ; hsa-mir-4760-5p ; hsa-mir-6778-5p ; hsa-mir-8061 ; hsa-mir-18a-5p ; hsa-mir-137 ; hsa-mir-18b-5p ; hsa-mir-548g-3p ; hsa-mir-4735-3p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-126-5p ; hsa-mir-4795-3p ; hsa-mir-450b-5p ; hsa-mir-570-5p ; hsa-mir-3915 ; hsa-mir-548ag ; hsa-mir-4459 ; hsa-mir-548ai ; hsa-mir-4476 ; hsa-mir-3689d ; hsa-mir-4710 ; hsa-mir-6851-5p ; hsa-mir-6876-5p ; hsa-mir-7854-3p ; hsa-mir-548ba ; hsa-mir-8066 ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-6165 ; hsa-mir-3152-3p ; hsa-mir-3928-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-6759-5p ; hsa-mir-6796-5p ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-376a-5p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-4648 ; hsa-mir-5589-3p

Nearest miRNA

hsa-let-7f-2/Upstream/229220; hsa-mir-105-1/Downstream/561032;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/153, chrX-CpG: 98/Downstream/297161

Upstream sequence

GGCGTGAGGTCTGGACCCCGGGGACCTGGCCTCAGGGAAGGGGGCGGGGAAAGCAGGTTGGAGCCTGAGACGTCTAAACTCCCGGCCCCGAACTTTCGCT

Downstream sequence

CGGGAACAAGGGATCCGGGGTCATGGGGAATAGGTCAGTGGGCCTTCAGCTCATGCtcctatcctagcactttctctcgctgtgtctatattgcagtctc