Basic Information
VIS ID
TVIS44024249
Fusion event
HTLV-1-PTCHD1-AS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
GRCh37/hg19
Start
23187779/23169662 (Hg38)
End
23187779/23169662 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
PTCHD1-AS
Nearest miRNA
hsa-mir-23c/Upstream/3152475; hsa-let-7f-2/Downstream/5325893;
Nearest TSS
ENST00000429181/Upstream/105543; ENST00000456522/Downstream/123484;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1228079, chrX-CpG: 25/Downstream/162505
Upstream sequence
TATATACGATCATGTCATTTATTCTACTTACTCTTGAGGCTGATCCTGTACAACTCTCTTACCAATTAGGGATGCCAGCTGTGGTAAAGTGAAAAGAGGA
Downstream sequence
CACAAAGGTTGAActatcaaatacaagctgtgtgatctacaataaacaagatcaaataattctgagcctccatttccttgtctgaagaatggaagacttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate