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TVIS44024276
Basic Information
VIS ID
TVIS44024276
Fusion event
HTLV-1-KLF8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
56050213/56023780 (Hg38)
End
56050213/56023780 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLF8
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-7977
;
hsa-mir-450a-1-3p
;
hsa-mir-342-3p
;
hsa-mir-383-3p
;
hsa-mir-1228-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-4728-5p
;
hsa-mir-6785-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-8075
;
hsa-mir-93-3p
;
hsa-mir-6826-3p
;
hsa-mir-4680-5p
;
hsa-mir-1236-3p
;
hsa-mir-6832-3p
;
hsa-mir-6515-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-3914
;
hsa-mir-5571-5p
;
hsa-mir-3152-5p
;
hsa-mir-6809-3p
;
hsa-mir-498
;
hsa-mir-6836-3p
;
hsa-mir-4753-3p
;
hsa-mir-6778-3p
;
hsa-mir-4772-3p
;
hsa-mir-1281
;
hsa-mir-4485-5p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-6877-3p
;
hsa-mir-6819-3p
;
hsa-mir-135a-5p
Nearest miRNA
hsa-let-7f-2/Upstream/572198; hsa-mir-105-1/Downstream/7762222;
Nearest TSS
ENST00000429181/Upstream/115657;
ENST00000476898/Downstream/208641;
Nearest CpG islands
None/Target,
chrX-CpG: 62/Upstream/534669
,
chrX-CpG: 17/Downstream/208738
Nearby gene
KLF8
(+208609) ;
Nearest cancer related gene
KLF8
(OG, No orient, 0)
Upstream sequence
ttgcaagagtttaatttttagagttctaaaaatgttgattttgagaattattaccagcattcttattgcttttatggaagaaaatatttttgcaggtctt
Downstream sequence
tactcccccttttcAAAAATCTCAACTCTTAGCAGActtttcaatggatgtaaagaatgtcattctatcaacatgctctgatgcatttattcagtaatct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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