VISDB Viral Integration Site DataBase

VIS ID

TVIS44024288

Fusion event

HTLV-1-AR integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chrX

Cytoband

q12

Reference genome

Start

End

66764362/67544520 (Hg38)

Orient

+

Location type

UTR5

Target gene

miRNAs that regulate target gene

hsa-mir-488-5p ; hsa-mir-124-3p ; hsa-mir-185-5p ; hsa-let-7b-5p ; hsa-mir-34a-5p ; hsa-mir-205-5p ; hsa-mir-2110 ; hsa-mir-491-5p ; hsa-mir-92a-2-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3148 ; hsa-mir-3153 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-552-3p ; hsa-mir-651-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4644 ; hsa-mir-4443 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-4693-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-5586-3p ; hsa-mir-190a-3p ; hsa-mir-205-3p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-381-3p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-4696 ; hsa-mir-31-5p ; hsa-mir-6786-3p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-3149 ; hsa-mir-297 ; hsa-mir-675-3p ; hsa-mir-3924 ; hsa-mir-6867-5p ; hsa-mir-8068 ; hsa-mir-223-5p ; hsa-mir-4307 ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-361-5p ; hsa-mir-589-3p ; hsa-mir-2115-3p ; hsa-mir-6868-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-4668-5p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-5193 ; hsa-mir-660-3p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-8085 ; hsa-mir-30c-1-3p ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-6871-5p ; hsa-mir-5010-3p ; hsa-mir-6809-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-3160-5p ; hsa-mir-4778-3p ; hsa-mir-320a

Nearest miRNA

hsa-let-7f-2/Upstream/1525541; hsa-mir-105-1/Downstream/2478337;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/285, chrX-CpG: 27/Downstream/1675

Nearest cancer related gene

AR(OG, No orient, 0)

Upstream sequence

ccaacccccctcaccacccttctccccacccgcccccccgcccccGTCGGCCCAGCGCTGCCAGCCCGAGTTTGCAGAGAGGTAACTCCCTTTGGCTGCG

Downstream sequence

AGCGGGCGAGCTAGCTGCACATTGCAAAGAAGGCTCTTAGGAGCCAGGCGACTGGGGAGCGGCTTCAGCACTGCAGCCACGACCCGCCTGGTTAGGCTGC