Basic Information
VIS ID
TVIS44024293
Fusion event
HTLV-1-BCYRN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
70832528/71612678 (Hg38)
End
70832528/71612678 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
BCYRN1
Nearest miRNA
hsa-let-7f-2/Upstream/1589755; hsa-mir-105-1/Downstream/2605699;
Nearest TSS
ENST00000429181/Upstream/3612; ENST00000636797/Downstream/5832;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/8425, chrX-CpG: 15/Downstream/103516
Upstream sequence
TTTCCCAGTTACGTTTTGCTGGGGCCTCCAAGTGGCTCTTCAGTGATTTTATAAGTAGATGGCTGTCTGAACTGAAGAGGAGAACCTCTCTCCTCCTTTC
Downstream sequence
CACGTTCTCTTTCTCCTTTCTCTTCCGTAATTTGAGCCGGCCTGACCACTGCTGCCGCTTGGTGCCCGGGTCTCTGACAACCCAGAGAAAAGTATTGCTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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