Basic Information
VIS ID
TVIS44024301
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
81025510/81770011 (Hg38)
End
81025510/81770011 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/2868762; hsa-mir-105-1/Downstream/2455741;
Nearest TSS
ENST00000429181/Upstream/514517; ENST00000373200/Downstream/1738250;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/766017, chrX-CpG: 63/Downstream/1738552
Nearby gene
SH3BGRL(+471464) ;
Upstream sequence
tggaactatgcAAATGGATGGTAGTTACTCCAGAAAAAAGTACATGTTACTGTTCTCTTATATTGTTAGAGATTATATATAAAAAAGGAGAAAGGGTGGC
Downstream sequence
TATCTAAAGAAGTGTTTTCCTCACAAATTCAAGCCATAAGAATAAAACAAGTATTATAACTGCTTGGTGTGTCCCTAAGTGGAAATCTGCAGTTTCATAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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