Basic Information
VIS ID
TVIS44024307
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
9269344/9301304 (Hg38)
End
9269344/9301304 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-1/Upstream/1174243; hsa-let-7f-2/Downstream/2017310;
Nearest TSS
ENST00000429181/Upstream/51384; ENST00000497555/Downstream/161991;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/499786, chrX-CpG: 22/Downstream/41374
Nearby gene
TBL1X(+161991) ;
Upstream sequence
ccaagggggcaattgctcagtggtacagtatttgcatgttttacggtggcaggattttgaagaatcatcaaTGCCAAGCTACAGGAGTTTGGATTTCAAA
Downstream sequence
GAATGGCATGAAAAGTGTTCACAAACTTTTGGGTAGACGGCATGTGATCAGAGTAGTCCCACATTAAAAGTAAGAATCCCGTGCAATATGGAGACCAAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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