Basic Information
VIS ID
TVIS44024328
Fusion event
HTLV-1-OLFM3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
102290857/101825301 (Hg38)
End
102290857/101825301 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1E
Target gene
OLFM3
miRNAs that regulate target gene
hsa-mir-10b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1543993; hsa-mir-11399/Downstream/6071922;
Nearest TSS
ENST00000473358/Upstream/185715; ENST00000414923/Downstream/11728;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/588112, chr1-CpG: 85/Downstream/1700169
Upstream sequence
ACGGGGATCAAAGGCAGGAGCTCGTCCATTTTCTCTTTCAACTCCTGTGAAAAGCAGCCTATTGTTCCTGAGAGTCATTTAAAACAGATCATGCTGCTCT
Downstream sequence
GTTCTTTTTATTATGATACTTAAAGGAAATTATTAAAACAGCTTCAACATTTCTTATTGATTTTTGGTTGAAATTAGGTATTTTGTGAAAATTTAAGCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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