Basic Information
VIS ID
TVIS44024345
Fusion event
HTLV-1-SARS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
109773817/109231195 (Hg38)
End
109773817/109231195 (Hg38)
Orient
-
Location type
Intronic
Target gene
SARS
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-29a-3p ; hsa-mir-26a-5p ; hsa-mir-1207-5p ; hsa-mir-1237-5p ; hsa-mir-1245b-3p ; hsa-mir-1909-3p ; hsa-mir-4488 ; hsa-mir-4506 ; hsa-mir-4525 ; hsa-mir-4697-5p ; hsa-mir-4716-3p ; hsa-mir-4763-3p ; hsa-mir-4790-3p ; hsa-mir-486-3p ; hsa-mir-5010-5p ; hsa-mir-5187-5p ; hsa-mir-636 ; hsa-mir-6721-5p ; hsa-mir-6722-3p ; hsa-mir-6741-5p ; hsa-mir-6794-5p ; hsa-mir-6798-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1333891; hsa-mir-11399/Downstream/367698;
Nearest TSS
ENST00000473358/Upstream/37; ENST00000468588/Downstream/5036;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16719, chr1-CpG: 109/Downstream/18128
Upstream sequence
tttGTAGAGAAACATAATCTGTTTAAAGAGGCCCACAGATCTACCAGTTGTACTTGCCTTTCTGCAAATGTATTGGCAATTAGATGCAATTCTCTTTCTA
Downstream sequence
AAGCAAGAGAGGGCTTATCAGGATTCCGTAGAACAAAAGCCACTAAGTGGTCCTCCATAATGAATGTCTGTTTTGCTGACtgaatcagaacagtctctgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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