Basic Information
VIS ID
TVIS44024354
Fusion event
HTLV-1-TSPAN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
115598607/115055986 (Hg38)
End
115598607/115055986 (Hg38)
Orient
-
Location type
Intronic
Target gene
TSPAN2
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4742-3p ; hsa-mir-452-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-1284 ; hsa-mir-664a-3p ; hsa-mir-6074 ; hsa-mir-5683 ; hsa-mir-4282
Nearest miRNA
hsa-mir-101-1/Upstream/2173857; hsa-mir-1182/Downstream/1504038;
Nearest TSS
ENST00000473358/Upstream/22623; ENST00000448680/Downstream/2439;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/200665, chr1-CpG: 72/Downstream/33243
Upstream sequence
taagggtctgtccagtgttttgttcttatgaataacatgtaatgagcatgatttgcacaaaaacgtctgtctgcatttctgattccttttccttagaata
Downstream sequence
aactccgagaagtggaatttctggatagaagggcataaacatacttaatcctctagtcttacatagtcatactgacctttaaaactatttactaatttct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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