Basic Information
VIS ID
TVIS44024369
Fusion event
HTLV-1-TNFRSF8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
12189860/12129803 (Hg38)
End
12189860/12129803 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
TNFRSF8
miRNAs that regulate target gene
hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-600 ; hsa-mir-4738-5p
Nearest miRNA
hsa-mir-12136/Upstream/100581; hsa-mir-101-1/Downstream/37140;
Nearest TSS
ENST00000473358/Upstream/3869; ENST00000536782/Downstream/37200;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/65712, chr1-CpG: 95/Downstream/37016
Upstream sequence
tctctctcagggcgtcctgccaggtttcgatgtctccctttcctggtgctgtgtactttgagcgctcgacggaggtgatgtcctgccgggcctctccact
Downstream sequence
gtgacgtctccatttgctcctcggtcattactaagtctttaggggcgttacttgagactatgtcaatagcccattcttcagcagaccttcattttctcta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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