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TVIS44024403
Basic Information
VIS ID
TVIS44024403
Fusion event
HTLV-1-EPHA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
16475353/16148858 (Hg38)
End
16475353/16148858 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA1A
Target gene
EPHA2
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-193b-3p
;
hsa-mir-34a-5p
;
hsa-mir-16-5p
;
hsa-mir-940
;
hsa-mir-520d-3p
;
hsa-mir-3187-3p
;
hsa-mir-1227-5p
;
hsa-mir-4435
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-548s
;
hsa-mir-5187-5p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-605-3p
;
hsa-mir-4509
;
hsa-mir-4744
;
hsa-mir-6754-5p
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-211-3p
;
hsa-mir-6757-5p
;
hsa-mir-1182
;
hsa-mir-2392
;
hsa-mir-3133
;
hsa-mir-186-5p
;
hsa-mir-124-3p
;
hsa-mir-302c-5p
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-4526
;
hsa-mir-8063
;
hsa-mir-3660
;
hsa-mir-888-3p
;
hsa-mir-200a-3p
;
hsa-mir-141-3p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-1197
;
hsa-mir-1273f
;
hsa-mir-128-1-5p
;
hsa-mir-128-2-5p
;
hsa-mir-1286
;
hsa-mir-3622b-5p
;
hsa-mir-3675-5p
;
hsa-mir-4253
;
hsa-mir-4436a
;
hsa-mir-4712-3p
;
hsa-mir-486-3p
;
hsa-mir-5000-3p
;
hsa-mir-6721-5p
;
hsa-mir-6762-5p
;
hsa-mir-6845-5p
;
hsa-mir-6862-5p
;
hsa-mir-6877-5p
Nearest miRNA
hsa-mir-12136/Upstream/3569835; hsa-mir-101-1/Downstream/710091;
Nearest TSS
ENST00000473358/Upstream/2408;
ENST00000424774/Downstream/6353;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/29
,
chr1-CpG: 89/Downstream/6131
Nearest cancer related gene
EPHA2
(OG, No orient, 0)
Upstream sequence
CGGGCGCAATGGTGTCAATCTTGGTGAACAGGCGCTTCTGGAAGTTGGTGCCGTAGTCCAGGTCCGACTCGGCATAGTAGAGGTTGAAAGTCTCCTTGCA
Downstream sequence
GGAGCTGGCGCCACCAGGGAAGCTGTTGCAGTCACGTACAGTAAACTTGAGCTCAATGAAGATACGCTCAGCCTCTCCTCGGTACACCCAGTTGGTGCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HTLV-1 carrier#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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