Basic Information
VIS ID
TVIS44024405
Fusion event
HTLV-1-NOS1AP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
162207795/162238005 (Hg38)
End
162207795/162238005 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOS1AP
miRNAs that regulate target gene
hsa-mir-423-5p ; hsa-mir-320a ; hsa-mir-6734-5p ; hsa-mir-4710 ; hsa-mir-7977 ; hsa-mir-6825-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-7854-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-3184-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-1197 ; hsa-mir-6768-5p ; hsa-mir-3692-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-3151-3p ; hsa-mir-138-2-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-888-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6730-3p ; hsa-mir-125b-2-3p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-3160-3p ; hsa-mir-4457 ; hsa-mir-513b-5p ; hsa-mir-5697 ; hsa-mir-6888-5p ; hsa-mir-708-5p
Nearest miRNA
hsa-mir-101-1/Upstream/80823; hsa-mir-1182/Downstream/104541;
Nearest TSS
ENST00000473358/Upstream/167915; ENST00000464284/Downstream/79789;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/167743, chr1-CpG: 43/Downstream/129081
Upstream sequence
CCTCTTGTCTGCCTCTGAGGGTGAAATGAGAGGAGTGTGAAGCACTTTGGGGTGTGGCCAGGCACACAGCTAGGCTCGATGCAGAGCTGCTGTCGTGGTG
Downstream sequence
GTGTGGCCCCAGTCATCATGAGCCACATCTGACAGGATTAATCACATTTCATATGCAAGCATGCTCTCTGCTTGACCGTGCTGTTGTTTTTAATGAGAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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