Basic Information
VIS ID
TVIS44024408
Fusion event
HTLV-1-NECAP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
16772094/16445599 (Hg38)
End
16772094/16445599 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
NECAP2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-149-5p
Nearest miRNA
hsa-mir-12136/Upstream/3866576; hsa-mir-101-1/Downstream/413350;
Nearest TSS
ENST00000473358/Upstream/4827; ENST00000509727/Downstream/9922;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4291, chr1-CpG: 126/Downstream/53044
Upstream sequence
tgCTGTAGGCTGAAGGAATCTTGGTGAGGTTGGAACACAAGGCAGATAAATTGACAAGAAACCACAGACTCTAGGGCTGTTGGTTTTGAATCAGTTCAGC
Downstream sequence
CTTGATTACAAAATTACCTCTTGCctgggcatggtagctcatgcctgtaatcctagcactttaggaggccaagacaggtggatcgcttgagcccaggaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate