Basic Information
VIS ID
TVIS44024416
Fusion event
HTLV-1-GPR161 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
168074433/168105195 (Hg38)
End
168074433/168105195 (Hg38)
Orient
+
Location type
Intronic
Target gene
GPR161
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-1307-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-4423-5p ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-4634 ; hsa-mir-4638-5p ; hsa-mir-504-3p ; hsa-mir-6501-5p ; hsa-mir-652-3p ; hsa-mir-6812-3p ; hsa-mir-744-3p
Nearest miRNA
hsa-mir-101-1/Upstream/106469; hsa-mir-1182/Downstream/270329;
Nearest TSS
ENST00000473358/Upstream/286; ENST00000367830/Downstream/29842;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/48711, chr1-CpG: 77/Downstream/30883
Upstream sequence
CCCTGACCAATTTCTTCCTCTGGTCTAACCCATCCTATCCATTTTCCCAAGACcagtggttcaaaacctttaatgtgctgaagaatcgtctgaagtgcca
Downstream sequence
gtttagaaagctgatccttgagctccaccactagaggttctgggcgcagagatcacaggcacaacctaggaatctgcattttaaacaagCAGGCTGGGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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