Basic Information
VIS ID
TVIS44024424
Fusion event
HTLV-1-PADI1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
17541874/17215379 (Hg38)
End
17541874/17215379 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
PADI1
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6077 ; hsa-mir-5580-5p ; hsa-mir-194-3p ; hsa-mir-1296-3p ; hsa-mir-6755-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929
Nearest miRNA
hsa-mir-12136/Upstream/356358; hsa-mir-101-1/Downstream/62510;
Nearest TSS
ENST00000473358/Upstream/10253; ENST00000483501/Downstream/8108;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/65799, chr1-CpG: 18/Downstream/192560
Upstream sequence
GTGGGGAGGGAGCAGATCTAGACTACAGGAAGCTAGGCTGGGCTTGGAGGGTCTTGATAGCCCCAGAGAAATTGTACCTGTCATTTCTTCCCCCTTCTTt
Downstream sequence
catcatcatcatcatcgtcatcatcatcatcatcatcatTTTCTACCAAGACTCCAAATAGGGGGCTGTGACTTAGAGATGTCAACTTTTGCCCAAAGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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