Basic Information
VIS ID
TVIS44024432
Fusion event
HTLV-1-TNR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
175594205/175625069 (Hg38)
End
175594205/175625069 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
TNR
miRNAs that regulate target gene
hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6830-3p ; hsa-mir-1250-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-6867-5p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-1257 ; hsa-mir-4666b ; hsa-mir-509-3p ; hsa-mir-580-5p ; hsa-mir-6818-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3480425; hsa-mir-1182/Downstream/343301;
Nearest TSS
ENST00000473358/Upstream/218705; ENST00000457217/Downstream/118547;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25397, chr1-CpG: 108/Downstream/581506
Upstream sequence
CTGGGGAGCTGCTAGATGAGGAAGCTCAATTGCACCTCTAGGGCCTCATCCTAAGCTTGGCCAGAAGTACTGGTGCTCCAGCACCAAGGAGCTAGCATCC
Downstream sequence
ATTGCAGCTTAAGAACTCTAGGGAAGAAGGGACCTCTACTTACCTGAAAAAGCTCCCAAGAGCCTTGAATAGCCACAAATTTGGCTTCTACGATTCCCAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate