Basic Information
VIS ID
TVIS44024433
Fusion event
HTLV-1-ARHGEF10L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
17966530/17640035 (Hg38)
End
17966530/17640035 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ARHGEF10L
miRNAs that regulate target gene
hsa-mir-324-5p
Nearest miRNA
hsa-mir-12136/Upstream/362060; hsa-mir-101-1/Downstream/1243167;
Nearest TSS
ENST00000473358/Upstream/282; ENST00000495593/Downstream/54012;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16860, chr1-CpG: 32/Downstream/56951
Upstream sequence
GCTCCTGGAGCCAGGCTGGGGAGCGTGGCTCAGCCACCCTGGCCAGGTACCTCCCTCTGGGGGTCATTGTGGGCGGAGGGATTCCTCCCCCAGGGGACCG
Downstream sequence
AGGCTTTGCCAAGCCACTGACCTCTTTGGCCACGTTTTGGGGATGCTCTGACCAGACCTCCTTGATCTCCAGGGCGCGTGGGTTGGAGGAAGTACTACGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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