Basic Information
VIS ID
TVIS44024471
Fusion event
HTLV-1-HP1BP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
21100508/20774015 (Hg38)
End
21100508/20774015 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
HP1BP3
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-193b-3p ; hsa-mir-29b-3p ; hsa-mir-382-3p ; hsa-mir-218-5p ; hsa-mir-7703 ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-4486 ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-1228-3p ; hsa-mir-6757-3p ; hsa-mir-1273e ; hsa-mir-219b-3p ; hsa-mir-25-3p ; hsa-mir-302f ; hsa-mir-3160-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4459 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-500a-3p ; hsa-mir-5186 ; hsa-mir-558 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-767-5p ; hsa-mir-7847-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-12136/Upstream/140227; hsa-mir-101-1/Downstream/214299;
Nearest TSS
ENST00000473358/Upstream/23764; ENST00000416959/Downstream/990;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/41142, chr1-CpG: 175/Downstream/12200
Upstream sequence
CAACAgatgcaatatggtatagtggaaaaaactcaagctcttaaagtcagaaaacctttgtttgtattttcactcaaacatttactagctagctatatga
Downstream sequence
tcttagtaaatgatgtgagtctttctcctcagctataaaacagtaatatagaaccaactatttcccaaggtgttgcaagaattataagagtatgtttatc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate