Basic Information
VIS ID
TVIS44024498
Fusion event
HTLV-1-PSEN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
227073131/226885430 (Hg38)
End
227073131/226885430 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
PSEN2
Nearest miRNA
hsa-mir-101-1/Upstream/963288; hsa-mir-1182/Downstream/1056160;
Nearest TSS
ENST00000473358/Upstream/807; ENST00000487450/Downstream/5136;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14225, chr1-CpG: 128/Downstream/53938
Upstream sequence
GAGCCACAGGTCTGTGGTCAGGGTGCCAGGAAATGAGCTGGAGGACAGGAACTGCTCATGGGGATGGTGCCCGCACTCCATCAGGGCAGCATGTGGGCAG
Downstream sequence
CATGGGCATCCCAGGCACCTCCCCTAGCAGGTCCAGAATCACTCAAGGTGGGGAGCCTCGAGGAGCAGTCAGGGCCGGGAGCATCAGCCCTTTGCCTTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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