Basic Information
VIS ID
TVIS44024507
Fusion event
HTLV-1-GALNT2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
230222418/230086671 (Hg38)
End
230222418/230086671 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
GALNT2
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-99b-3p ; hsa-mir-7855-5p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-1909-5p ; hsa-mir-432-5p ; hsa-mir-5690 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-6813-3p ; hsa-mir-3200-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1624519; hsa-mir-1182/Downstream/933157;
Nearest TSS
ENST00000473358/Upstream/19412; ENST00000492568/Downstream/168687;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/18209, chr1-CpG: 24/Downstream/192925
Upstream sequence
AGCAGTTTTTTTTTCCCCCGTGTGTTAAGGGAATTTATTTTCCTTTTCATTCTTTGTTCCTCCTTGGCTCACCCCTGCTCAGGACATAACTTTTGCAGAA
Downstream sequence
ATGAGGATTTTGCTGCAGCCTGAATCTCCTGGGTTGGATCTCTTAGAGCAATTAATAACTTGTTATTCATGTGTTCGGGGCACAGCCCTTTGTACTCAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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