Basic Information
VIS ID
TVIS44024509
Fusion event
HTLV-1-COG2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
230818409/230682663 (Hg38)
End
230818409/230682663 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
COG2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2220511; hsa-mir-1182/Downstream/337165;
Nearest TSS
ENST00000473358/Upstream/39852; ENST00000482012/Downstream/1660;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/39816, chr1-CpG: 119/Downstream/185222
Upstream sequence
GTGTCTTCAGTGCTCAGCTGTGTTGGGTAGGGCTGCTGCTTTTTGTCTCAAGCTGTTCTTTTTACTCTTCAGACAGTTGCCTTTAGCTCAGTCTGTGAAC
Downstream sequence
CGCTTTGTAAAAGCACATTATGTACTATAAAAAATAATTTAATATCAGTTGGATAAATTGATATTGAGCATGCATCAGAATTCATTACTAGTAAGGCAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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