Basic Information
VIS ID
TVIS44024524
Fusion event
HTLV-1-ADSS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
244613053/244449751 (Hg38)
End
244613053/244449751 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
ADSS
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-96-5p ; hsa-mir-20a-5p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-548aj-5p ; hsa-mir-2116-5p ; hsa-mir-4273 ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-548j-3p ; hsa-mir-2113 ; hsa-mir-4772-5p ; hsa-mir-20a-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4495 ; hsa-mir-2115-3p ; hsa-mir-548av-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548c-3p ; hsa-mir-383-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-6739-3p ; hsa-mir-22-5p ; hsa-mir-6881-5p ; hsa-mir-6782-5p ; hsa-mir-181c-3p ; hsa-mir-5582-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1103496; hsa-mir-3124/Downstream/2752216;
Nearest TSS
ENST00000473358/Upstream/24837; ENST00000464170/Downstream/2383;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/394515, chr1-CpG: 103/Downstream/1399
Upstream sequence
AAGACTAATAAAGAATCCTAATGATACACTTTTAAAAAGCACTAAAAGAACATAAGGATTCTATAAGGAAGGTAGTTAAGTCAAAAATACACAGGTGAGG
Downstream sequence
GAAGTCTGCCCAACAAGGCCCCTCATTTGTTTCTCCACTATCTTCAGCTAACATTTTAAAGCCAAACTTAGTTCCTTCTCAATCACTTCTCTAGCCTTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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