Basic Information
VIS ID
TVIS44024527
Fusion event
HTLV-1-SMYD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
245974238/245810936 (Hg38)
End
245974238/245810936 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
SMYD3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2464681; hsa-mir-3124/Downstream/1391031;
Nearest TSS
ENST00000473358/Upstream/21994; ENST00000426386/Downstream/3475;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/121724, chr1-CpG: 132/Downstream/163537
Upstream sequence
CTGCCAAAGCCACGTGGCCGAGCAGACGGAGGGAGTGCAGTCTCCACACTGAGGCTGACTGAAAACATAAATAACTAGGCAAGATTTTTCAGTAGCTAGT
Downstream sequence
GAGGTTATCACATACTCTGGACAAAATCCCTAGTGCTCATTACACTTCTGATATGATTTTCTCACCTCTCTCCAGGCTCACTGATGCATCTTCCAATTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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