Basic Information
VIS ID
TVIS44024531
Fusion event
HTLV-1-SCCPDH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
246890418/246727116 (Hg38)
End
246890418/246727116 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
SCCPDH
miRNAs that regulate target gene
hsa-mir-15b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3380861; hsa-mir-3124/Downstream/474851;
Nearest TSS
ENST00000473358/Upstream/3069; ENST00000567832/Downstream/45185;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2390, chr1-CpG: 34/Downstream/61796
Upstream sequence
CCCTTCTTTGTATCAGAACAAACAATCCATTCATTTCTAGCAAAATATTCCAGAGGAACATAAGGACAGAGGACAGAATTGTTGGTTGAAGGCCTTAACC
Downstream sequence
CCATATGGGGAGTTTTTTCTTCTTGCGAGGAGCAGCTGGAGATGACCAAAGTCTCCTGAGAGAGTGAGTGACAGGCTCTCCATGACGTTCTCCTTAGGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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