Basic Information
VIS ID
TVIS44024535
Fusion event
HTLV-1-NUDC integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
27228712/26902221 (Hg38)
End
27228712/26902221 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
NUDC
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-296-3p ; hsa-mir-484 ; hsa-mir-483-3p
Nearest miRNA
hsa-mir-12136/Upstream/347628; hsa-mir-101-1/Downstream/3836935;
Nearest TSS
ENST00000473358/Upstream/1755; ENST00000452707/Downstream/11745;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1703, chr1-CpG: 71/Downstream/19336
Nearby gene
GPATCH3(-1750) ;
Upstream sequence
gtgagttaggtaagactggtgtatgcccctctggttcaccaatgacaaagccagacacagactccatattccaaatctcctcatgaaagctttgaggaac
Downstream sequence
ttcttgtccccactgatcagttggaacaaactttggttaaaacttctctccttcccccagcttcccgaactttggcttaccctcagcttgagccagcgca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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