Basic Information
VIS ID
TVIS44024562
Fusion event
HTLV-1-NDUFS5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
39495277/39029605 (Hg38)
End
39495277/39029605 (Hg38)
Orient
+
Location type
Intronic
Target gene
NDUFS5
miRNAs that regulate target gene
hsa-mir-1296-5p ; hsa-let-7e-5p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-589-5p ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-890 ; hsa-mir-1255b-2-3p
Nearest miRNA
hsa-mir-12136/Upstream/940276; hsa-mir-101-1/Downstream/1724750;
Nearest TSS
ENST00000473358/Upstream/3287; ENST00000484793/Downstream/51711;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/38006, chr1-CpG: 142/Downstream/51362
Upstream sequence
CAGGTTAGAAATTGCATGTGTGTGTATACCCATTTTTTCAGTTGGCTGTGAAGCAGAGAATATCAACTAGTTTTGGATGTTGACCCTTGAAAATCTTTGG
Downstream sequence
GTGAAAATATGTTCAAATCCATTGAATCCTCATTGGAAAAGAGGTTTAACCTTGCAAATCCATTACATTCAACATCTTTGGATTCATTCCACTCTGAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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